It does like your computer - otherwise it wouldn't run there at all. What it apparently does not like is where you install or run it.
I suggest that you leave it at that and keep the free MED copied in your Gamestudio folder. It's a slightly never version than 6.50, but has all its features, so you can start it from there. Maybe later some other user runs into a similar problem and then we can find out more about the reason.