For sound/sample creation, editing, recording, mastering, effects and atmo:
NI-Reaktor
http://www.nativeinstruments.de/index.php?reaktor_us&ftu=397ca2c98c3459d&flash=9
It´s the best and powerful software synth/sampler/effect if you ask me. You are able to construct any possible and impossible sound machines.

For bones animation and seamless export to mdl7:
Fragmotion
http://www.fragmosoft.com/