i don't think it would work with lite-c because the acknex.dll needs to be bound to the python.exe and as far as i know only the gamestudio editions can do that.

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it could be that it works with the lite-c editions too if you work directly in the lite-c directory. the acknex.dll security mechanism checks if some files are present in the same directory (like sed.exe and some others) and if it finds them it probably doesn't have to be bound to python.exe.
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originally my plan was to do the wrapper for gamestudio first (in order to learn how all of this wrapping stuff works) and later move it to ogre or irrlicht. an open source solution with gamestudio-like scripting would be nice. but it would be a lot of work which i have procrastinated so far.