i wouldnt use TUSC, because i cant scream at it in anger if it doesnt do waht i want. but i cans cream at people XD
also, im usually not against 3rd party plugins if it makes sense. im waiting for iridium engine for example.
id like to have more plugins that takes the engine further, graphically, because in ameplay, one can buy any code from a good coder.
but good AI helbs, so does good path finding or maybe a cutscene creator :p