Sorry, but i think Blender will remain Blender,
The basic gizmos, windows selection (3D, VU) etc ... are the SAME.

They just added windows, stack of operations or visible operation buttons : Blender remains the same for the most part
you must choose the same icons as before !

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For your questions, go ot "user preferences" you can choose
mouse control like in "Maya" !

Just played with it , lot of 3D format export are lacking !
Even FBX i've tested was buggy and the model after import
in MED was screwed up !

I had to use BLender 2.49 to export FBX for MED !

So be carefull with thi release

But WELL it's great for :
- UV
- animations
- standard modeling
And it's FREE !!