Gamestudio is guaranteed to run on all normal PCs. The specs listed above are very low, so almost every PC fulfils them.
However, there are of course many ways to create a project that runs nowhere and crashes often. You'll find in the manual under "Publish" or "Starting the engine" what DLLs you must include with your project. They are normally automatically included, so you don't need to care. Only when you rely on external software, such as Codecs required for playing your music or video, you have to know what you do. When you tell that your music crashes often, the problem might lie in that area. Otherwise, use the -diag option to get some info from your users what the problem is - the music, your script, or something else.