Since it is in your windows folder it IS an important file and might be use by different programs. Is there a repair function for the IE? Or try to upgrade the IE to a newer version if possible. Or download a ieframe.dll from the internet and temporarily replace it (save the old file!). Threre are different possibilities for you. Have you ever done a virus check on your system? The ieframe.dll should work wihtout any errors. Maybe you can do an MD5 check to see if the file has been edited by some non authorized program.