Well, I remember George did something like that in one of the AUMs where the program checked the ID of an optical drive to see if it was the intended recipient. But that being said, most indie developers shouldn't get themselves worked up over piracy prevention because it's not going to work very well anyways; even the big publishers can't prevent people from pirating their games and software. Save yourself some effort and put it into a making the next great game. Goodluck!