It's possible and runs very fast with *.X faster than *.3ds without the posibillity of smoothing groups.
But I don't know how this could be done.
I have made two screenshots of an example with a normal sphere (only the smoothing groups are modified). The sphere has 2 smoothing groups the upper half is group 1 the lower half has goup 2 and the left half group 1 and 2. All this is working in Quest 3D in realtime.

Here is an example out of 3D Studio Max:


Here is an example after export with panda X exporter and import it into Quest 3D with smoothing groups: