3DGS can do the bulk of it. You'll need an external image edittor (GIMP - it's free and very good) for making your textures if you want custom textures other than those provided, and some sort of music/sound edittor to get music and sound effects (FL Studio is great for this) if you don't want to use what is already supplied. Other than that, 3DGS has everything.

"You level up the fastest and easiest if you do things at your own level and no higher or lower" - useful tip My 2D game - release on Jun 13th; My tutorials