The .wad format is different, as it supports 32-bit textures inside the wad. From what I know, you're limited to 256-colors for HL and Quake...I know when I have "Quake" selected as the game when using QuArK to make maps, it will not let me use the "standard.wad" for 3dGS.
^_^
"We've got a blind date with destiny...and it looks like she's ordered the lobster."