What sort of industry are you targeting? If you are trying to secure a contract in the PC game or console game industry, then the publisher will require that you have a proven track record of previous games. I remeber the days when you could develop games in your garage, but since the consolidation, game development is a big deal.

If you are looking to break in to the casual games maerket, then you should look at alawar, or real arcade. They are always looking for people with good ideas, or a brilliant demo.

There are also a lot of books and resources on the net on game design, and getting your game published. In any case, it is a highly competetive industry and difficult to succeed in.