Blender's interface is a lot more confusing than MED's at a glance, and as you start with it, but I can say that after having used both, that Blender is far superior. Even having keyboard shortcuts makes everything quicker.
Plus, you get all the features in one free package - I only have 3DGS Extra, so no bones in MED. Blender does bones, all sorts, physics, fluid simulation... all right, I'll stop advertising

Blender is very flexible, at the cost of being more confusing.
I find that for UV mapping, I just select the faces, then rotate the camera so they appear as I want them UV mapped, then unwrap them in the 'from window' mode. Lets you do large numbers of faces easily and accurately.