Hi Matt !
Infact PCXANI68.exe is not a standalone application. It is an updated exe for for PCXANIM as packed in Pcxanim_1.7.zip downloadable from my post earlier here (July 2017). The exe file in the zip package needs to be replaced with PCXANI68.exe. The exe needs the prospeed.dll and color map to run properly from its folder. OK, I confess it is a bit missleading to offer the last PCXANI68 Version that nacked. So it should run then on Win10, I tested PCXanim on some machines with WinXP and Win7 and had no problems.
I also have a GOLD Version in mind to be compiled with some new features and a more friendly user interface. Well if I only had a second life.