DOF in Gothic3 looked bad and it was the first feature I switched off. It also does not make much sense to have a great visible distance in a game while you are not able to see sharp at that distance. Since you dont know where the player looks at you cannot focus the dof distance unless you do eyes tracking with additional hardware.

In an image or in a cut scene you can use this effect to force the player to look at the sharp region. So it makes more sense in this situation.