@losticmate : it depends on your cartoon style in fact
It's not like people targetting realistic look where lot lot lot of things must be respected to make it look life like ( mass effect characters etc ...) Yes low poly is really easy and fast, and fun caus you don't care about details , proprotions, you can express your imagination.
Another way is making high resolution cartoon sculpting (look at my next zombie posts) , than retopology and bake normal map for texture guide ! Sculptris is the king for that