Hi alun, based on the manual, you need to put minus sign not in front of each UK100 row, but in front of the OptimalF in each UK100 row. That is the first collumn of parameters, example for USD/CAD in the manual text below :

"How can I add new assets or exclude assets from trading?

Z8, Z9, Z10 can be used with any portfolio of stocks and ETFs. The other systems are optimized for a particular set of assets; you can not add, but you can exclude assets from trading. For excluding a certain component from trading in Z1, Z2, Z12, or Z7, edit Data\Z12.fac or Data\Z7.fac and place minus signs '-' in front of its OptimalF factors. The algorithms with the ES, HU, LP, LS, VO identifiers belong to Z1, A2, BB, CT, CY, HP to Z2, and PA, PD, PDD, PG to Z7. An example for excluding the CT algorithm with the USD/CAD asset:

USD/CAD:CT -.041 1.32 263/420
USD/CAD:CT:L -.029 1.25 177/227
USD/CAD:CT:S -.058 1.38 86/93"